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The Role of Creatine In the Body

Thursday, May 21, 2015 11:47:05 AM Europe/London

For so long Creatine has been in the category of supplements relegated to the world of sports for an increase of muscle mass and strength. Hence knowledge on its immense capabilities has eluded the general population. The benefits of Creatine are evident in the fields of medicine to research its ability to help with neuromuscular problems like muscular dystrophy.

So what is Creatine?

Creatine production in the body is by the combination of three amino acids: arginine, methionine, and glycine. It is stored in the body as Creatine phosphate in very little amounts and to reach the amounts contained in Creatine supplements naturally, then one has to eat a huge chunk of foods that contain high amounts of Creatine like beef and salmon.

The body’s main source of energy is Adenosine Tri-Phosphate (ATP), formed within the cells in an organelle known as the Mitochondrion. Creatine is responsible to the production of ATP. Therefore, aging as a process and most disease states is huge because of the energy supplies of the body not being commensurate to the breaking down of molecules through oxidative processes within the body. Therefore maintain a healthy state is hinged on being able to prevent the levels of ATP from depleting and reducing the oxidative processes of the cell through the mitochondrial breakdown of DNA. In fact, most people take anti-aging nutrients for their ability to maintain optimum production of ATP and reduced rates of oxidation.

The workings of Creatine

Highly active tissues and organs in the body like the heart and the brain are sensitive to reduced amounts of ATP, which impedes their performance, and Creatine has emerged the best in maintaining and even increasing the amounts of ATP.

Creatine as earlier mentioned is stored in the body as Creatine phosphate or phosphocreatine. In addition, in generating of energy, the ATP molecule loses a molecule of Phosphate to become Adenosine Diphosphate (ADP). Phosphocreatine donates one phosphate molecule to the ADP, making it ATP again and the more Phosphocreatine molecules then, the faster the transformation of ADP back to the energy molecule ATP.

Creatine use is vital in short-duration sports, like sprinting or weight lifting that require a burst of energy. Creatine plays a major role in protein synthesis and cell hydration. Creatine is available in different chemical combinations, but Creatine monohydrate is so far the most used due it high absorptive rate of up to 90%. Others are Creatine citrate and Creatine phosphate.

Benefits of Creatine

Since Creatine is vital in the production of ATP, what good does this do to the body? Research has come to show that Creatine administered to patients suffering from various forms of muscle dystrophy has led to improved conditions like the increase of strength in the muscles, which in turn betters the functionality of that muscle and alleviates the symptoms of the diseases.

The brain has proved to be the organ where the effects of Creatine are beaming as it can keep the brain from stress neurological injuries, and this is majorly by the protecting the brain from toxins like beta-amyloid and injuries like those caused from by the inadequate supply of oxygen to the neurons as seen in  most strokes.

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Posted Thursday, June 4, 2015 1:06:31 PM Europe/London

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